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Inhibition of NF-κB Delays Senescence and Aging

A groundbreaking study on aging has been published in the Journal of Clinical Investigation. The scientists set out to understand how DNA damage and aging are related.  It is believed damage to DNA...

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Novel Screening Method Finds New Potent Anti-Aging Compound

Scientists in Japan have developed and reported a new methodology for assessing the chronological lifespan of yeast.  These single celled eukaryotes are often used in lifespan experiments as the basic...

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Methylene Blue May Improve Mitochondrial Health and Increase Lifespan

Mitochondrial dysfunction appears to play an important role in aging.  As these crucial intracellular organelles become damaged by the ROS they create, they become less efficient leading to more ROS...

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New Study Confirms Rapamcycin Extends Lifespan in Normal Mice

Rapamycin may very well be the first drug capable of potently slowing the aging process. It is known to target a critical cellular switch called mTOR.  This switch controls several lines of cell...

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Newly Created Synthetic Mitochondrial Targeted Antioxidant Found to be Effective

The aging process is at least in part due to due accumulative cellular damage inflicted by reactive oxygen species (ROS). This ROS is mostly created by the mitochondria as they metabolize glucose and...

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Beta Blockers Extend Lifespan

Adrenaline, also known as epinephrine is the fight of flight hormone.  Cells throughout the body have receptors for this compound and its effect on cell function are myriad. There is an increasing body...

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New Klotho Enhancing Anti-Aging Drugs in Development

A protein called Klotho is known to be important in cellular aging pathways.  It might be considered an anti aging protein; when it is knocked out in animal models those organisms show accelerated...

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Anti Aging Drug Breakthrough Achieved

Publishing his work in the prestigious journal Science, David Sinclair of Harvard reports a breakthrough in the development of drugs that can block the aging process. The article is entitled Evidence...

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Drugs to Safely Slow Aging May be on the Horizon

It is fairly safe to say that medications which will slow the aging process are coming soon. Though an important school of thought, proposed by de Grey, is that we are better off repairing and...

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Caffeine Extends Lifespan Through Key Cell Pathway

There is solid and ever growing evidence that regular coffee consumption is associated with reduced risk of many age-associated diseases including cardiovascular disease, cancer, diabetes, and...

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Can GnRH Administration Reduce Aging?

Gonadotropin releasing hormone (GnRH) is produced in a deep seated region of the brain called the hypothalamus. The hormone functions to stimulate the sex glands to release sex hormones, mostly...

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Scientists Find Compound Reverses Aging in Mice

Recently the media has covered on a story about research in mice where it is claimed aging is reversed. The story originated from the lab of David Sinclair, a Harvard researcher, and is based on a...

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